Threats to national and economic security are increasingly complex, aggressive, and intertwined. Supply chain vulnerabilities in critical sectors, cybersecurity risks, and gaps in traditional defense capabilities have the potential to destabilize and endanger both state and commercial entities. Coordinated and transparent multilateral engagement between like-minded allies will be critical in countering these issues, and in ensuring the strength and security of national and economic systems. Yet the importance of transnational cooperation will need to be balanced against growing voices for protectionism in exports and imports of sensitive technologies across sectors. How can state and business agents work jointly to prevent a schism between commercial and security interests?